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PDB Keyword
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PF01933

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

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    Resources
    Pfam ID: UPF0052 PDB: 2hzb_A
    Solved by: NESG Priority Score: 2.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 1347 # architectures: 3 # taxonomy ids:833
    FFAS:
      Top FFAS hit in PDB: "2hzbA, Hypothetical UPF0052 protein BH3568" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2p0yA, structural genomics, unknown function ; crystal structure of q88yi3_lacpl from lactobacillus plantarum. northeast structural genomics consortium target lpr6 "
    CATH: CATH Domain E-value CATH Node
      2hzbA00 1.40E-84
      3c3dA01 6.00E-43 3.40.50.10680
      3c3dA02 4.30E-08 1.10.8.240
    FUNFAM (eval=0 ): Putative uncharacterized protein At2g34090 -like
    PUBSERVER:
      Publications(s) found: 986
      Publications(s) meeting filtering criteria: 14
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2p0y_A SCOP: predicted c.143.1.1 ECC: predicted 2.8.-.-
    FFAS: PDB: 2hzb_A
    MGENTHREADER: PDB: 2o2z_A
    PRC: PDB: 2hzb_A
    BLASTP: PDB: 2o2z_A
    HHBLITS: PDB: 2o2z_A
    COMPASS: PDB: 2hzb_A
    CSBLAST: PDB: 2p0y_A SCOP: predicted c.143.1.1 ECC: predicted 2.8.-.-
    HHSEARCH: PDB: 2o2z_A
    E.coli Annotations
    NCBI: 16128748 PORTECO PORAL: ybhK GeneExpDB: b0780

    Topsan Members

    Tag pages as 'PF01933' to appear in this list.

    Name Annotation Author(s)
    3cgw

    Summary

    Pfam family

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    {Uncharacterized protein family UPF0052 } with 1089 members in NR database and additional 682 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota.

    The first structural representative solved (PDB Id:

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    ) was subject to FATCAT structural similarity search that yielded no results, thus suggesting that it is a novel fold. SCOP classifies 2hzb, a member of the UPF0052, in the alpha/beta class, CofD-like fold and (super)family. Using 3cgw as query, DALI provides hits with other UPF0052 structures like 2hzb, 2o2z, 2ppv, 2q7x, and 2p0y (Z=23-17).

    Based on a previously described function/ original paper, this family is a 2-phospho-(L)-lactate transferase [Ref].

    Reviews

    References

     

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