The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Topsan Members

    Tag pages as 'PF01796' to appear in this list.

    Name Annotation Author(s)
    Gene SSO2064 from Sulfolobus solfataricus encodes the NP_343458 protein belonging to the DUF35 family (PF12172 rubredoxin, and PF01796 OB fold). STRING genome context analysis shows two 0.9 scored hit... pascual (5 edits)
    krishna (3 edits)


    Pfam family PFAM:PF01796 {Domain of unknown function DUF35 } with 1010 members in NR database and additional 561 members in the metagenomic datasets is represented in Archaea, and Bacteria.

    The first structural representative solved (PDB Id: TOPSAN:3irb) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1ueba3 classified as OB-fold fold. Profile-profile methods confirm a remote homology between this family and the superfamily of nucleic acid binding domains belonging to the OB-fold. A Dali search with 3irb provides only weak hits (Z-scr=4) with OB-fold proteins from the ethanolamine utilization operon (EutN)  like 2hd3, 2z9h, and 2qw7.

    Based on remote homology confirmed by the structure, one can hypothesize that this family binds nucleic acids [Ref].




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