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PF01170

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: UPF0020 PDB: 3k0b_A
    Solved by: BSGC Priority Score: 5.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 8543 # architectures: 113 # taxonomy ids:1713
    FFAS:
      Top FFAS hit in PDB: "1o9hA, RRNA METHYLTRANSFERASE" Top FFAS hit in Pfam: "PF11599, RRNA methyltransferase AviRa "
    GRDB:
      Top significant hit (PDB90): "3ldgA, transferase ; crystal structure of smu.472, a putative methyltransferase complexed with sah "
      Top significant hit (PFAM25U): "PF10672, S-adenosylmethionine-dependent methyltransferase"
    CATH: CATH Domain E-value CATH Node
      2avdA00 1.20E-05
      3gjyA00 0.0059 3.40.50.150
    FUNFAM (eval=0 ): Type I restriction enzyme EcoR124II M protein -like
    PUBSERVER:
      Publications(s) found: 1422
      Publications(s) meeting filtering criteria: 83
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    FFAS: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    MGENTHREADER: PDB: 2as0_A SCOP: predicted c.66.1 ECC: 2.1.1.-
    PRC: PDB: 1o9g_A SCOP: c.66.1.29
    BLASTP: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    HHBLITS: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    COMPASS: PDB: 3evz_A SCOP: predicted c.66.1.54 ECC: predicted 2.1.-.-
    COMA: PDB: 3k0b_A SCOP: predicted c.66.1
    CSBLAST: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    HHSEARCH: PDB: 3ldu_A SCOP: predicted c.66.1 ECC: predicted 2.1.-.-
    E.coli Annotations
    NCBI: 16128915 PORTECO PORAL: rlmL GeneExpDB: b0948

    Topsan Members

    Tag pages as 'PF01170' to appear in this list.

    Name Annotation Author(s)
    1vq1
    The TM0488 gene from Thermotoga maritima encodes a N5-glutamine methyltransferase, HemK (EC 2.1.1.-) (PF01575, COG2890). The TM0488 structure adopts an S-adenosyl-L-methionine dependent methyltransfe... tinab (4 edits)
    krishna (1 edits)

    Summary

    Thid domain is predicted with a high confidence to be N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]. It also shares significant similarity with class I S-adenosylmethionine-dependent methyltransferases.

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