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  Featured Annotation
2q9k:

The Exig_1997 gene from Exiguobacterium sibiricum 255-15 gives several strong, but possibly misleading hints to encode for a pyridoxamine 5'-phosphate oxidase (PF01243, cl00381), an enzyme which catalyzes the reaction of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). The structure adopts a beta roll (2q9k-CATH). There is high structural similarity to several oxidoreductases like 1r1z [Ref] and PSI target 2ou5. Significant sequence homology to 2e83 (chain A), 3f7e (chain A) is detected by HHpred. ...


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Developer Update – January 2010
We are currently improving TOPSAN performance issues on a development site.  Two of the primary features that were slowing down TOPSAN were the external real-time feeds on protein pages and advanced search options. These features have been disabled but will be back in the next TOPSAN upgrade.  We are expecting to upgrade TOPSAN within the [...]
Adding References on TOPSAN
We recently added a new feature on TOPSAN that allows you to easily add references as you are editing a protein page. To use this feature, 1. Select the pubmed icon in the WYSIWYG tool bar while in edit-mode: 2. A dialog box will appear that allows you to enter a Pubmed Id, ISBN number, or keyword [...]
 
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  PSI Statistics
  PDB Other
JCSG 952 4565
MCSG 1016 885
NYSGXRC 695  
SECSG 88  
ATCG3D 11  
BSGC 88  
CESG 113  
CSGID 100  
ISFI 13  
NESGC 626  
BIGS 8  
BSGI 57  
ISPC 14  
RSGI 2724  
XMTB 11  
SSGCID 11  
TBSGC 93  

 

 
 
 
 
 
 
 
 
 
 
 
 

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Reviews

References

 

  1. van den Heuvel RH, Westphal AH, Heck AJ, Walsh MA, Rovida S, van Berkel WJ, and Mattevi A Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformation and support novel mechanism of action. J Biol Chem. 2004 Mar 26; 279(13):12860-7 PubMed HubMed doi:10.1074/jbc.M313765200 pmid:14703520.

     


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